GPT-5.5 autonomously spent 150+ hours improving protein folding models.
Summary
GPT-5.5 autonomously spent over 150 hours improving protein folding models, showcasing advanced AI-driven scientific research.
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@ChrisHayduk: GPT 5.5 is an effective autoresearcher in structural biology! I've had goal mode running for over 150 hours straight, l…
A user reports that GPT 5.5 successfully conducts autonomous research in structural biology, improving AlphaFold2's performance after 150+ hours of goal mode.
Introducing GPT-5.5
OpenAI has released GPT-5.5, a significant upgrade to its frontier AI model, boasting superior capabilities in agentic coding, research, and multi-step task execution while maintaining efficiency and speed.
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Early experiments in accelerating science with GPT-5
OpenAI releases a research paper documenting early experiments where GPT-5 accelerates scientific discovery across mathematics, physics, biology, and other fields, including cases where the model helped identify disease mechanisms, solve open problems, and improve optimization algorithms in collaboration with leading universities and national laboratories.
Introducing GPT-5.1 for developers
OpenAI releases GPT-5.1, a new model in the GPT-5 series that dynamically adapts thinking time based on task complexity, offering 2-3x faster performance than GPT-5 while maintaining frontier intelligence. The release includes extended prompt caching (24-hour retention), new coding tools (apply_patch and shell), and a 'no reasoning' mode for latency-sensitive applications.