M^{2}SNet: Multi-scale in Multi-scale Subtraction Network for Medical Image Segmentation

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Summary

This paper proposes M2SNet, a multi-scale multi-scale subtraction network for medical image segmentation that uses subtraction operations to capture difference features between encoder levels, improving localization and edge sharpness. It achieves state-of-the-art performance on eleven datasets across four medical imaging modalities.

Accurate medical image segmentation is critical for early medical diagnosis. Most existing methods are based on U-shape structure and use element-wise addition or concatenation to fuse different level features progressively in decoder. However, both the two operations easily generate plenty of redundant information, which will weaken the complementarity between different level features, resulting in inaccurate localization and blurred edges of lesions. To address this challenge, we propose a general multi-scale in multi-scale subtraction network (M^{2}SNet) to finish diverse segmentation from medical image. Specifically, we first design a basic subtraction unit (SU) to produce the difference features between adjacent levels in encoder. Next, we expand the single-scale SU to the intra-layer multi-scale SU, which can provide the decoder with both pixel-level and structure-level difference information. Then, we pyramidally equip the multi-scale SUs at different levels with varying receptive fields, thereby achieving the inter-layer multi-scale feature aggregation and obtaining rich multi-scale difference information. In addition, we build a training-free network ``LossNet'' to comprehensively supervise the task-aware features from bottom layer to top layer, which drives our multi-scale subtraction network to capture the detailed and structural cues simultaneously. Without bells and whistles, our method performs favorably against most state-of-the-art methods under different evaluation metrics on eleven datasets of four different medical image segmentation tasks of diverse image modalities, including color colonoscopy imaging, ultrasound imaging, computed tomography (CT), and optical coherence tomography (OCT). The source code can be available at https://github.com/Xiaoqi-Zhao-DLUT/MSNet.
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Paper page - M^{2}SNet: Multi-scale in Multi-scale Subtraction Network for Medical Image Segmentation

Source: https://huggingface.co/papers/2303.10894 Published on Mar 20, 2023

Abstract

A multi-scale subtraction network (M^\{2\}SNet) enhances medical image segmentation by capturing detailed and structural cues, improving localization and edge sharpness compared to traditional methods.

Accuratemedical image segmentationis critical for early medical diagnosis. Most existing methods are based onU-shape structureand useelement-wise additionorconcatenationto fuse different level features progressively in decoder. However, both the two operations easily generate plenty of redundant information, which will weaken the complementarity between different level features, resulting in inaccurate localization and blurred edges of lesions. To address this challenge, we propose a general multi-scale in multi-scale subtraction network (M^{2}SNet) to finish diverse segmentation from medical image. Specifically, we first design a basicsubtraction unit (SU)to produce the difference features between adjacent levels in encoder. Next, we expand the single-scale SU to theintra-layer multi-scale SU, which can provide the decoder with both pixel-level and structure-level difference information. Then, we pyramidally equip the multi-scale SUs at different levels with varyingreceptive fields, thereby achieving theinter-layer multi-scale feature aggregationand obtaining rich multi-scale difference information. In addition, we build a training-free network ``LossNet’’ to comprehensively supervise thetask-aware featuresfrom bottom layer to top layer, which drives our multi-scale subtraction network to capture the detailed and structural cues simultaneously. Without bells and whistles, our method performs favorably against most state-of-the-art methods under different evaluation metrics on eleven datasets of four differentmedical image segmentationtasks of diverse image modalities, includingcolor colonoscopy imaging,ultrasound imaging,computed tomography (CT), andoptical coherence tomography (OCT). The source code can be available at https://github.com/Xiaoqi-Zhao-DLUT/MSNet.

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