6x MI50's on PCIE vs 4x MI50's on PEX8749 and 2x on PCIE

Reddit r/LocalLLaMA News

Summary

A user benchmarks AMD MI50 GPUs across different PCIe configurations on an older X99 motherboard, comparing direct PCIe connections vs using a PEX8749 switch. Results show minimal performance difference with slight improvement in token generation speed.

I am really excited to share this one. On the X99-E-WS motherboard.. while old and PCIE 3.0 - I think it's still pretty capable for what I'm trying to do (1TB VRAM across 3 machines). The board has seven physical PCIe x16 slots shared through the onboard PEX8747 PCIe 3.0 switches and with a 40 lane CPU + all seven slots populated, the board supports an x16/x8/x8/x8/x8/x8/x8. What I tested was putting a PEX8749 card on the x16 slot so that 4x MI50's ran on the switch thus freeing up 3 PCIE slots for additional cards. Online data is scarce for folks running the PEX8749 card and Claude/ChatGPT gave me conflicting answers on wether this would increase tg/pp speeds or decrease tg/pp speeds so I figured I'd just test the before and after. Hardware: Asus X99-E-WS (Modded BIOS to support a large number GPU's ) Intel(R) Xeon(R) CPU E5-2680 v4 @ 2.40GHz 128GB DDR4 RAM SSD Model: dervig/m51Lab-MiniMax-M2.7-REAP-139B-A10B @ Q3_L Here are the results: Test 6× MI50 all direct 4× PLX + 2× direct Difference Change pp512 139.27 138.24 −1.03 −0.74% tg128 24.87 25.55 +0.68 +2.73% pp512+tg128 71.12 72.47 +1.35 +1.90% pp4096+tg128 120.95 120.96 +0.01 +0.01% pp16384+tg128 117.69 117.27 −0.42 −0.36% pp32768+tg128 103.56 103.64 +0.08 +0.08% pp65536+tg128 81.99 82.67 +0.68 +0.83% I ran llama bench multiple times and surprisingly tg was always just a smidge better .8% ~ 2.8% with the PP speed loss at less than 1%.
Original Article

Similar Articles

P40's + MI50's + RPC on 550B Nemotron Ultra Q3_S

Reddit r/LocalLLaMA

User shares benchmark results running the 550B Nemotron Ultra model across two machines using RPC, achieving impressive throughput on older AMD MI50 and Nvidia P40 GPUs.

I tested the CMP170HX

Reddit r/LocalLLaMA

A hands-on benchmark of Nvidia CMP170HX mining cards repurposed as 64GB VRAM AI inference accelerators, showing they can run large local LLMs like DeepSeek V4-Flash and gpt-oss-120B at useful speeds, with caveats around Ampere-class throughput and PCIe Gen2 x4 connectivity.