I benchmarked RAG techniques on a synthetic healthcare database. The biggest gains came from document shape, not model tweaks.

Reddit r/LocalLLaMA Papers

Summary

A benchmarking study on RAG techniques using a synthetic healthcare database found that optimizing document shape provided larger performance gains than adjusting model parameters.

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When Retrieval Doesn't Help: A Large-Scale Study of Biomedical RAG

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A large-scale study across 5 models (7B–72B), 10 biomedical QA datasets, 4 retrieval methods, and 4 corpora finds that RAG yields only small and inconsistent gains (1–2 points) over no-retrieval baselines in biomedical question answering. The study concludes that the main bottleneck is not retrieval quality but models' limited ability to effectively use retrieved evidence.