Position: AI Agents in Scientific Teams Should Be Studied as Human-Agent Systems

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Summary

This position paper argues that AI agents in scientific teams should be studied as human-agent systems to enhance collaboration and mitigate risks such as reduced diversity in scientific inquiry.

Large language model-based agents are increasingly deployed as collaborators in scientific discovery yet most current work focuses on the autonomous capabilities of "AI Scientists". We argue that this overlooks the social aspects of scientific teamwork, and that studying AI Scientists as human-agent systems (HAS)--where the unit of analysis is the human-agent pair--is both underexplored and undervalued. We establish these points through literature and empirical analysis, and highlight recent incidences and studies which show that deploying agents in science without accounting for human-agent dynamics introduces near-term risks, including reduced diversity of scientific inquiry. Through analysis of real-world case studies, we show that scientists and agents can augment each other's capabilities. We call for new research that adopts the HAS lens to develop mathematical frameworks for understanding and fostering human-AI synergy in scientific discovery.
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Source: https://huggingface.co/papers/2608.14667 Published on Aug 2

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Submitted byhttps://huggingface.co/LeoYML

Leo Yon Aug 18

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Abstract

Scientific collaboration with AI agents requires studying human-agent pairs to avoid risks like reduced inquiry diversity and to foster synergistic discovery.

Large language model-based agentsare increasingly deployed as collaborators in scientific discovery yet most current work focuses on the autonomous capabilities of “AI Scientists”. We argue that this overlooks the social aspects of scientific teamwork, and that studyingAI Scientistsashuman-agent systems(HAS)--where the unit of analysis is the human-agent pair--is both underexplored and undervalued. We establish these points through literature and empirical analysis, and highlight recent incidences and studies which show that deploying agents in science without accounting forhuman-agent dynamicsintroduces near-term risks, including reduced diversity of scientific inquiry. Through analysis of real-world case studies, we show that scientists and agents can augment each other’s capabilities. We call for new research that adopts the HAS lens to develop mathematical frameworks for understanding and fosteringhuman-AI synergyin scientific discovery.

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