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NASA's Nancy Grace Roman Space Telescope features an experimental coronagraph with adaptive optics technology, aiming to directly capture starlight reflected off exoplanets for the first time, representing a major advancement in space-based astronomy.
The article presents MOSAIC, a multimodal adaptive optical microscope capable of switching between various imaging modalities (widefield, light-sheet, two-photon, etc.) and applying adaptive correction for sample-induced aberrations, enabling imaging from single molecules to whole organisms in vivo.