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This paper introduces TIER-MoE, a risk-guided subspace mixture-of-experts model for multimodal biomedical classification that estimates sample-specific modality reliability from out-of-fold predictions and routes modalities to experts, improving performance and calibration on four public datasets.
This paper systematically evaluates five imbalance handling methods (RUS, ROS, SMOTE, re-weighting, direct F1 optimization) on three biomedical datasets (tabular, text, image) using models of varying complexity. Results show that benefits depend on model complexity and data modality, with ROS, re-weighting, and direct F1 optimization being effective for complex models on unstructured data.