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Research suggests bones may release proteins that slow aging and extend life span, pointing to skeletal signaling as a potential factor in longevity.
OpenAI的数千个GPT-Rosalind智能体在32分钟内分析了数百万个小鼠脑细胞，完成了人类预计需要数月至一年的研究工作，并为神经退行性疾病发现新线索，75%的情况下人类专家更偏好其研究结果。
IEEE Spectrum reports that organ-on-a-chip technologies, pioneered by Donald Ingber's Harvard Wyss Institute lung-on-a-chip, are finally gaining mainstream adoption as alternatives to animal testing in drug development and toxicology.
ReviewPilot is a conversational multi-agent system that automates the PRISMA systematic review workflow from paper screening to information extraction, using project memory to retain configurations and providing source-backed decisions. It outperforms single-prompt LLM and AgentSLR baselines across three LLMs, achieving screening macro F1 up to 0.776 and extraction F1 up to 0.788, with case studies showing transferability to biomedicine and HCI.
Stanford researchers published in Science a method to regrow cartilage and prevent arthritis by blocking the age-related protein 15-PGDH, showing reversal of cartilage loss in mice and promising results in human tissue samples.
This research paper investigates how creatine uptake enhances antitumor immune responses, based on scientific findings in immunology and oncology.
The article discusses how AI could dramatically accelerate biomedical research, creating a bottleneck where current clinical trial and regulatory processes may delay patient access to new treatments, calling for urgent adaptation to the pace of AI-driven discoveries.
The Trump administration plans to give Russell Vought, head of the OMB, veto power over all NIH grants, a move that could politicize biomedical research funding. This follows previous attempts to control NIH grants, which faced legal and congressional pushback.
The article reports on AI BioDesign, a project using artificial intelligence and experiments to create molecules not found in nature, led by Nobel laureate David Baker, aiming to advance medicine and technology.
The paper introduces PASS, an agentic AI system that predicts publication venues for manuscripts by analyzing literature context, achieving high accuracy and outperforming baselines, and is released as a public platform for researchers.
Researchers have identified a genetic mutation named PIN in malaria parasites that reduces sensitivity to common antimalarial drugs, spreading rapidly in Uganda and threatening malaria control efforts.
Researchers at MIT and colleagues have developed a new mRNA adjuvant that boosts T-cell responses to vaccines, demonstrating promising results in mouse models for cancer and infectious diseases, which could lead to more effective treatments.
An MIT-developed medical database evolved into PhysioNet, a global biomedical data repository used by thousands of researchers worldwide, as detailed in a recent Nature Health paper.
An HIV vaccine developed by La Jolla Institute for Immunology and Scripps Research has shown unprecedented success in generating broadly neutralizing antibodies in primates, with human trials now underway.
Researchers are exploring agentic AI as co-scientists that can independently assist with ideation, hypothesis generation, and accelerating scientific exploration in biomedical research.
DeepMind's Co-Scientist AI tool bridges the expertise of two researchers from different biological fields to accelerate ALS research by generating testable hypotheses and identifying RNA-based mechanisms for potential therapies.
Researchers developed new antibiotics from scorpion venom and habanero peppers, demonstrating efficacy against resistant bacteria including tuberculosis strains, with ongoing work towards clinical trials.