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Eric Topol highlights a BMJ study showing tirzepatide (Zepbound) reduces cardiovascular events, infections by 36%, and all-cause mortality by 45% compared to sitagliptin in diabetic patients with prior atherosclerotic cardiovascular disease.
MyoCardBench is a real-world benchmark for evaluating large language models in cardiovascular care, comprising 2,263 items across 13 tasks. GPT-5.4 achieved the highest overall score, demonstrating strengths in full-cycle care and multimodal interpretation.
A study of over 1 million VA patients found that the updated 2024–2025 COVID-19 vaccine still provides significant protection against cardiovascular events like heart attack and stroke, especially in people over 75 and those with underlying conditions.