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科学家通过将80岁人类的红血球前体细胞直接重编程为神经干细胞，成功将细胞的表观遗传年龄逆转了60年以上，研究成果发表于《Aging Cell》期刊。
研究人员成功将80岁老年供体的血细胞重编程为干细胞，其分子层面的年龄特征降至20岁以下，显示细胞重编程可大幅逆转生物学年龄。
A Phase 1 trial reports what may be the first successful rejuvenation of human eye cells, using three Yamanaka factors delivered as proteins to reprogram damaged retinal ganglion cells in glaucoma patients, based on David Sinclair's epigenetic reprogramming theory.