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This case report documents transient multidomain functional improvements in an advanced Alzheimer's patient following high-dose psilocybin administration, with recovery of speech, continence, and social interaction over days to weeks.
This paper proposes a large language model-driven data augmentation framework using GPT-5 to generate synthetic oral monologues from written anchors for cognitive score prediction from speech. A similarity-guided selection strategy consistently reduces prediction error, particularly for minority low-score participants.
Routine vaccines like those for flu, shingles, and Tdap are linked to lower dementia risk, with a new hypothesis suggesting they may train the innate immune system, previously thought untrainable, offering potential new avenues for dementia prevention.