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Mr.Dec: Daily-Scale Longitudinal Multimodal Modeling for 30-Day Readmission Prediction

arXiv cs.LG · yesterday Cached

Mr.Dec is a multimodal Transformer-based model that sequences daily Electronic Health Record updates and chest X-ray findings to predict 30-day hospital readmissions, achieving state-of-the-art results on MIMIC datasets.

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Logit-Boundary Geometric Belief Interfaces and Sparse Sheaf-Enclave Protocols: A Self-Contained Substrate for Secure Network Electronic Health Record (EHR) Interoperability

arXiv cs.AI · 2026-08-12 Cached

This arXiv paper proposes a mathematical and engineering architecture, the Geometric Belief Interface, for secure EHR interoperability using logit boundaries and sheaf-enclave protocols, with a narrow benchmark showing zero coverage for a 4B model.

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CliniCARE-Bench: Clinical Calibrated Audit of Medical Reasoning in EHR

arXiv cs.AI · 2026-08-11 Cached

Introduces CliniCARE-Bench, a deployment-oriented benchmark for evaluating AI agents on clinical audit tasks over longitudinal EHR data, with 25 clinician-validated scenarios and 750 patient cases. It assesses verdict accuracy, evidence grounding, policy adherence, and calibrated abstention, finding that raw accuracy overstates investigation quality.

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A Comparative Study of Feature Selection Methods for EHR Diagnosis Codes in Opioid Use Disorder Prediction

arXiv cs.LG · 2026-08-06 Cached

This paper compares five feature selection methods for EHR diagnosis codes in opioid use disorder prediction, finding that NTK sensitivity offers the best accuracy-stability balance while LLM-guided selection adds complementary clinical signals.

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Pretraining EHR Foundation Models with Patient-Aware Sampling

arXiv cs.LG · 2026-07-27 Cached

Proposes Patient Sampling, a pretraining sequence construction method for EHR foundation models that improves downstream performance over the standard Global Stream baseline on MIMIC-IV datasets, highlighting the importance of sequence construction in autoregressive health models.

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CardioMeta: Calibrated Multi-Task Prediction of Diabetes, Hypertension, and Cardiovascular Disease Across Population and EHR Data

arXiv cs.LG · 2026-07-20 Cached

CardioMeta is a calibrated multi-task framework for jointly predicting diabetes, hypertension, and cardiovascular disease across NHANES and MIMIC-IV data, emphasizing leakage control, calibration, and transparent reliability.

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LLM4EHR: Aligning Clinical Time Series with Medical Event Sequences via Large Language Models

arXiv cs.LG · 2026-07-20 Cached

LLM4EHR proposes a clinical foundation model that temporally aligns Electronic Health Record time series with medical event sequences using a domain-adapted large language model and a regularized contrastive objective, improving downstream prediction tasks.

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Multimodal Routing for Interpretable, Robust, and Auditable Clinical Prediction

arXiv cs.LG · 2026-07-14 Cached

This paper proposes an explicit multimodal routing framework for clinical prediction using EHR data, enabling interpretable, robust, and auditable reasoning across structured variables, clinical notes, and chest X-rays via discrete unimodal, bimodal, and trimodal routes with inference-time route masking for missing modality simulation.

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Evaluating Retrieval-Augmented Generation vs. Long-Context Input for Clinical Reasoning over EHRs

arXiv cs.CL · 2026-07-13 Cached

This paper evaluates retrieval-augmented generation (RAG) versus long-context prompting for clinical reasoning tasks over electronic health records, finding RAG to be token-efficient and competitive, especially for imaging extraction and antibiotic timeline reconstruction.

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How Should Transformers Encode Numeric Values in Electronic Health Records?

arXiv cs.LG · 2026-07-03 Cached

This paper systematically compares discrete, continuous, and hybrid value encoding strategies for transformers in electronic health record data, finding that hybrid token-based approaches with binning provide robust performance and are recommended as a practical default.

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PORTER: Language-Grounded Event Representations for Portable Structured EHR Foundation Models

arXiv cs.CL · 2026-06-24 Cached

PORTER is a language-grounded structured EHR foundation model that represents clinical events through text descriptions and numeric values, enabling vocabulary-independent transfer across institutions without retraining. On pediatric prediction tasks, PORTER matches fixed-vocabulary models and recovers 97.1% of AUROC when transferred to unseen event descriptions.

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Are LLMs Ready to Assist Physicians? PhysAssistBench for Interactive Doctor-Patient-EHR Assistance

arXiv cs.CL · 2026-06-18 Cached

Introduces PhysAssistBench, a benchmark for evaluating LLMs in interactive doctor-patient-EHR assistance. Experiments show current models are unreliable in this setting, highlighting the need for coordinated capabilities.

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AIPatient Arena: EHR-grounded evaluation of large language models in end-to-end clinical consultation workflows

arXiv cs.CL · 2026-06-17 Cached

Introduces AIPatient Arena, an EHR-grounded evaluation framework for assessing LLMs across multiple dimensions of clinical competence. The study reveals strengths in interviewing and ethics but weaknesses in handling ambiguity and diagnostic accuracy.

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A Machine-Learned Comorbidity Index

arXiv cs.AI · 2026-06-17 Cached

This paper proposes a Machine-Learned Comorbidity Index (MLCI) that uses diagnosis codes and nonlinear learning to improve risk adjustment across multiple clinical outcomes, outperforming traditional mortality-centric indices.

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Hierarchical Modeling of ICD Codes in EHR Foundation Models

arXiv cs.AI · 2026-06-16 Cached

This paper investigates explicit encoding of ICD-10-CM hierarchy in EHR foundation models, using hierarchical token augmentation and graph-based code representations. Experiments on MIMIC-IV and eICU show improvements over flat code representations for in-domain and cross-dataset prediction tasks.

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Accelerating Reproducible Research in Synthetic EHR Generation

arXiv cs.LG · 2026-06-08 Cached

This paper introduces a lightweight, end-to-end benchmarking framework for reproducible synthetic Electronic Health Record (EHR) generation, unifying multiple baselines (MedGAN, CorGAN, PromptEHR, HALO) and a GPT-2 baseline under a single pipeline with a rigorous privacy-utility evaluation suite.

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Traj-Evolve: A Self-Evolving Multi-Agent System for Patient Trajectory Modeling in Lung Cancer Early Detection

arXiv cs.AI · 2026-06-03 Cached

This paper presents Traj-Evolve, a self-evolving multi-agent system that uses an experience pool and multi-agent reinforcement learning to model patient trajectories from longitudinal EHRs for lung cancer early detection, outperforming strong baselines.

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ChatHealthAI: Aligning Electronic Health Record Representations with Large Language Models for Grounded Clinical Reasoning

arXiv cs.AI · 2026-06-03 Cached

ChatHealthAI is a multimodal reasoning framework that aligns structured EHR representations with a frozen LLM to enable grounded clinical reasoning while maintaining predictive performance.

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Towards Error-Free EHRs: Reasoning-Intensive Consistency Verification Between Clinical Notes and Structured Tables in Electronic Health Records

arXiv cs.CL · 2026-05-27 Cached

This paper introduces EHR-ReasonCon, a reasoning-intensive benchmark for consistency verification between clinical notes and structured tables in electronic health records, and EHR-Inspector, an LLM-based framework that achieves state-of-the-art performance in detecting discrepancies.

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TreeText-CTS: Compact, Source-Traceable Tree-Path Evidence for Irregular Clinical Time-Series Prediction

arXiv cs.LG · 2026-05-21 Cached

Introduces TreeText-CTS, a method that converts irregular EHR trajectories into compact, source-traceable tree-path evidence units without patient-level summarization. Achieves state-of-the-art AUROC and AUPRC among text-based EHR time-series interfaces on three clinical benchmarks.

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