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Phorecaster365: A Human-Supervised Reference Architecture for Hybrid Pharmaceutical Sales Forecasting and Planning Decision Support

arXiv cs.CL ↗ · 2026-09-15 Cached

Phorecaster365 presents a human-supervised reference architecture for pharmaceutical sales forecasting that integrates data ingestion, modeling, and governance with a validation framework, though it does not establish real-world accuracy.

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#ensemble-modeling

@beckypferdehirt: Most PDB structures show one frozen conformation. But proteins are not static. New work from @stephanie_mul at @radials…

X AI KOLs Timeline ↗ · 2026-08-12 Cached

Researchers reprocessed ~80,000 high-res PDB structures with qFit to recover hidden conformational heterogeneity, producing over 60,000 multiconformer models — the largest experimentally derived ensemble dataset to date, with improved fit in ~90% of cases.

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