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文章比较了 DNA 语言模型(如 Evo 2)与 AlphaGenome 在预测 DNA 变异影响上的差异:前者基于序列似然评分,后者基于实验测量预测基因表达与剪接等读出,且仅限研究用途。
A new DNA synthesis method called Sidewinder dramatically reduces cost and time to build genetic sequences, enabling rapid construction of AI-designed genomes with high accuracy.