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In a thread, @agupta agrees with @JTLonsdale's suggestions on the US biotech crisis and adds that the US should aggressively expand the research university system and 10x NIH and NSF budgets to leverage AI.
US biotech is in crisis as China surpasses the US in blockbuster pharma deals; the next FDA Commissioner must overhaul the agency and beat China to unleash cures.
Paperclip adds over 220K FDA regulatory documents and 1M clinical trials from multiple registries, enabling AI agents to search and reason over clinical and regulatory data without web search. This update allows users to query FDA documents, ClinicalTrials.gov, and international registries via a unified filesystem interface.
The FDA launches a pilot program using Causal AI to shorten clinical trial timelines for drugs and medical devices, potentially reducing trial duration by 20-40% and speeding regulatory approval.