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EMBER 提出一种无需对接复合物结构的 TCR–pMHC 结合预测框架,将 TCR 与 pMHC 独立折叠并编码为 SE(3) 不变残基图进行比较,避免了对接误差的传播,同时降低计算复杂度,并在表位不相交评估中全面超越六个基线模型。
This research paper investigates how creatine uptake enhances antitumor immune responses, based on scientific findings in immunology and oncology.
A large-scale Shigella outbreak in research primates provided valuable immunological data, revealing new targets for vaccine development against this common bacterial pathogen.
An HIV vaccine developed by La Jolla Institute for Immunology and Scripps Research has shown unprecedented success in generating broadly neutralizing antibodies in primates, with human trials now underway.
The Arc Institute hosted its 3rd Annual Investigator Retreat, featuring talks on genome engineering, generative protein models, computational biology, and deep dives into neurodegeneration, immunology, and metabolism.
OpenAI's GPT-5 Pro helped immunologist Derya Unutmaz solve a three-year-old mystery about how glucose affects T cell specialization by suggesting that deoxyglucose interferes with IL-2 protein construction, leading to increased inflammatory Th17 cells.
Researchers at the University of Cambridge have developed the first entirely AI-designed vaccine, which targets entire virus families and has successfully completed a Phase I human trial showing safety and broad immune response.
Immunologist Derya Unutmaz discusses in the podcast how he used OpenAI's Codex and reasoning models to build complex biological simulation applications (such as flow cytometry analysis tools, T-cell receptor simulators), and looks forward to the future of AI-driven 'virtual cells' and digital twins.