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The article discusses the advancement of therapeutic cancer vaccines using personalized mRNA technology, highlighting recent positive Phase 3 results for melanoma and ongoing trials for other cancers, with potential approvals expected by 2027.
A new peer-reviewed study published in Gut Microbes found that a single intravenous dose of the frog-derived gut bacterium Ewingella americana completely eradicated tumors in 100% of mice with colorectal cancer, outperforming chemotherapy and immune checkpoint blockade while showing no toxicity.
New University of Calgary research shows that knocking out a single gene makes colon cancer cells visible to the immune system, and when combined with immunotherapy, leads to 100% tumor eradication in mouse models, offering a potential new approach for treating colorectal cancer.
Pioneering Australian melanoma doctor Richard Scolyer has died at 59 after undergoing a world-first experimental immunotherapy treatment for glioblastoma. His work with Georgina Long dramatically improved survival rates for advanced melanoma patients.
Researchers are testing CAR T cell therapy, originally designed for cancer, as a treatment for autoimmune diseases like multiple sclerosis, aiming to reset the immune system. The article follows a patient who received the experimental treatment.