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TriGlue: a Biology-Inspired Generative Model for Generating Molecular Glue-Induced Ternary Complex

arXiv cs.LG ↗ · 2026-07-27 Cached

TriGlue is a biology-inspired generative model that designs molecular glue-induced ternary complexes by first predicting protein-protein interfaces and then generating molecular glues conditioned on the interface, enabling targeted protein degradation.

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