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该论文提出两种闭式投影算子,可在推理时直接修正 AlphaFold3 风格扩散模型输出中的物理无效结构(链间碰撞、键长畸变、非平面环、手性翻转),无需重训练或额外网络评估,在 Boltz-2 与 OpenFold-3 上实现完美的物理有效性同时保持结构精度。
This paper introduces Tianmu-TC, a physics-constrained generative AI framework for global tropical cyclone forecasting that outperforms traditional systems in reliability and computational efficiency.