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New HIV vaccine shows unprecedented success in preclinical study

Hacker News Top · 4d ago Cached

An HIV vaccine developed by La Jolla Institute for Immunology and Scripps Research has shown unprecedented success in generating broadly neutralizing antibodies in primates, with human trials now underway.

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#preclinical-study

Single Dose of Frog-Derived Gut Bacterium Eradicates 100% of Tumors in Mice

Hacker News Top · 2026-07-01 Cached

A new peer-reviewed study published in Gut Microbes found that a single intravenous dose of the frog-derived gut bacterium Ewingella americana completely eradicated tumors in 100% of mice with colorectal cancer, outperforming chemotherapy and immune checkpoint blockade while showing no toxicity.

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#preclinical-study

Memory decline after menopause linked to loss of estrogen production in brain

Hacker News Top · 2026-05-30 Cached

A new preclinical study suggests that loss of estrogen production in the brain after menopause may disrupt the extracellular matrix in the hippocampus, offering a potential explanation for why women face higher Alzheimer's risk.

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