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本文提出 PIDiff,一种联合离散序列空间与 SE(3) 结构流形扩散的多模态框架,用于蛋白质-蛋白质复合物设计,并提出 PIFormer 架构与 PIBench 数据集,在 minibinder 和抗体设计任务上超越基线方法。
Anthropic AI announced that Claude successfully designed novel protein binders for 14 out of 15 drug targets, with independent verification by Adaptyv Bio and Twist Bioscience.