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Pepti-Agent is a closed-loop AI framework for therapeutic peptide design that uses MCP tools and an LLM controller to iteratively refine sequences based on multi-property profiles, addressing constraints like solubility, hemolysis, and non-fouling.
OpenAI 与 Retro Biosciences 合作开发了 GPT-4b micro,这是 GPT-4o 的专门版本,用于蛋白质工程,实现了干细胞重编程标志物表达提高 50 倍,并增强了 DNA 损伤修复能力。这些发现已在多个供体和细胞类型中得到验证,证明了人工智能加速生命科学研究的潜力。