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A startup named Generation Lab claims to have developed an injectable drug called 1-Generation that reverses aging in blood, but the article highlights concerns about unproven evidence and red flags in their clinical trial approach.
This paper investigates the loss of model plasticity after excessive supervised fine-tuning (SFT) in the SFT-then-RL pipeline for LLMs, and proposes Rejuvenation, a method that restores plasticity via base-anchored model fusion and targeted neuron reset, consistently improving RL performance.
David Sinclair plans to test an oral epigenetic reprogramming drug, SL-100, in the XPrize competition for whole-body rejuvenation, aiming for a 10-year age reversal.