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Researchers at Stanford and the Arc Institute used AI models Evo 1 and Evo 2 to design hundreds of novel bacteriophage genomes, 16 of which produced fully functional viruses capable of infecting E. coli. The breakthrough opens new avenues for combating antibiotic resistance but raises biosecurity concerns.
Researchers used large genome models Evo 1 and Evo 2 to design new bacteriophage genomes, producing viruses with distinct features challenging to evolve naturally, raising questions about potential future design of vertebrate-targeting viruses.
US researchers used generative AI models Evo1 and Evo2 to design complete virus genomes for the first time, creating 16 novel bacteriophages that can kill E. coli. The breakthrough could enable new disease treatments but raises urgent safety and security concerns.