Taiwanese company Skymizer announces HTX301 - PCIE inference card with 384GB of Memory at ~240 Watts

# Skymizer Announces HTX301 — Reinventing On-Prem AI Inference Source: [https://skymizer.ai/skymizer-announces-htx301-reinventing-on-prem-ai-inference/](https://skymizer.ai/skymizer-announces-htx301-reinventing-on-prem-ai-inference/) [Skip to content](https://skymizer.ai/skymizer-announces-htx301-reinventing-on-prem-ai-inference/#content)- [Categories](https://skymizer.ai/skymizer-announces-htx301-reinventing-on-prem-ai-inference/#) ## Skymizer Announces HTX301 — Reinventing On\-Prem AI Inference  **Skymizer today announced HTX301**, the first reference chip built on the HyperThought™ platform — redefining how enterprises deploy and scale AI inference\. For the first time,**ultra\-large models can run on a single PCIe card**\. Powered by**six HTX301 chips and 384GB of memory**, enterprises can now execute**700B\-parameter LLM inference locally at just ~240W**— eliminating the need for massive GPU clusters, NVLink/NVSwitch interconnects, and complex cooling infrastructure\. Built for the new era of inference\-dominant AI, HyperThought™ introduces a fundamentally different approach\. By**disaggregating prefill and decode workloads**and pairing**decode\-first silicon**with an intelligent software orchestration stack, HTX301 enables**higher utilization, lower latency, and significantly improved power efficiency**across real\-world deployments\. *HyperThought™*scales seamlessly from**on\-device to on\-prem environments**under a unified architecture powered by LISA™ \(Language Instruction Set Architecture\), allowing enterprises to**right\-size deployments from 4B to 700B models without over\-provisioning\.** The result is a new class of AI infrastructure:**data sovereignty, predictable cost, and deterministic performance**— unlocking agentic AI workflows across enterprise applications without the hidden tax of per\-token cloud inference\. “***Inference has become the dominant AI workload, and infrastructure needs to reflect that reality\.******The era of needing superscalar GPU clusters for ultra\-large LLMs is over\. HyperThought shifts AI from hyperscaler\-only complexity to single\-card simplicity for every enterprise\.***“ — William Wei, Chief Marketing Officer, Skymizer “***Purpose\-built decode hardware paired with an intelligent software stack that orchestrates every inference workload — that’s how you disaggregate P/D at scale\.***” — Luba Tang, Chief Technology Officer, Skymizer As AI models scale from**billions to trillions of parameters**, HTX301 marks a decisive step beyond brute\-force GPU scaling — delivering a**simpler, more efficient, and enterprise\-ready path to AI deployment\.** #### Continue Reading  ## Headquarters 12F\-2, No\.408, Ruiguang Rd\., Neihu Dist\., Taipei City 11492, Taiwan ## Hsinchu Office Center of Innovative Incubator R819, No\. 101, Section 2, Kuang\-Fu Road, Hsinchu, Taiwan © 2026 • Skymizer Taiwan Inc\. [Page load link](https://skymizer.ai/skymizer-announces-htx301-reinventing-on-prem-ai-inference/#)