BioInsight: Multi-Agent Orchestration for Interactive Biomedical Knowledge Discovery

Hugging Face Daily Papers Papers

Summary

BioInsight is a multi-agent system that transforms static biomedical reports into interactive, evidence-centered interfaces by organizing disease-specific evidence through structured artifacts and deterministic citation normalization.

Biomedical researchers increasingly use AI-generated analyses and reports to interpret protein-level signals, but static outputs are often insufficient for research decision-making, where users need to inspect evidence, assess uncertainty, compare mechanisms, and refine hypotheses. We present BioInsight, a multi-agent system that moves from static biomedical report generation to interactive evidence-centered interactive interface generation. Given a disease name, a protein association table, and optional cohort metadata, BioInsight organizes disease-specific evidence through typed intermediate artifacts, including ranked pathways, literature evidence packets, protein-level reasoning notes, citation-grounded reports, dashboard schemas, and rendered interactive interfaces. The system decomposes evidence retrieval from mechanistic reasoning, normalizes citations through deterministic components, and converts the same structured evidence used in the report into an interactive interface. We evaluate BioInsight on standardized biomedical QA, challenging protein-function reasoning, and end-to-end biomedical evidence synthesis. Results show that BioInsight achieves best, and suggest that biomedical AI systems should move beyond text-only and static reports toward provenance-preserving, interactive evidence artifacts.
Original Article
View Cached Full Text

Cached at: 07/02/26, 03:46 AM

Paper page - BioInsight: Multi-Agent Orchestration for Interactive Biomedical Knowledge Discovery

Source: https://huggingface.co/papers/2606.20997 Published on Jun 19

·

Submitted byhttps://huggingface.co/Joysw909

Wangon Jul 2

Authors:

,

,

,

,

,

,

,

,

,

Abstract

BioInsight is a multi-agent system that transforms static biomedical reports into interactive, evidence-centered interfaces by organizing disease-specific evidence through structured artifacts and deterministic citation normalization.

Biomedical researchers increasingly use AI-generated analyses and reports to interpret protein-level signals, but static outputs are often insufficient for research decision-making, where users need to inspect evidence, assess uncertainty, compare mechanisms, and refine hypotheses. We present BioInsight, amulti-agent systemthat moves from static biomedical report generation to interactive evidence-centered interactive interface generation. Given a disease name, aprotein association table, and optional cohort metadata, BioInsight organizesdisease-specific evidencethroughtyped intermediate artifacts, includingranked pathways,literature evidence packets,protein-level reasoningnotes,citation-grounded reports,dashboard schemas, and renderedinteractive interfaces. The system decomposesevidence retrievalfrommechanistic reasoning, normalizes citations throughdeterministic components, and converts the same structured evidence used in the report into an interactive interface. We evaluate BioInsight on standardizedbiomedical QA, challengingprotein-function reasoning, andend-to-end biomedical evidence synthesis. Results show that BioInsight achieves best, and suggest that biomedical AI systems should move beyond text-only and static reports toward provenance-preserving, interactive evidence artifacts.

View arXiv pageView PDFProject pageAdd to collection

Get this paper in your agent:

hf papers read 2606\.20997

Don’t have the latest CLI?curl \-LsSf https://hf\.co/cli/install\.sh \| bash

Models citing this paper0

No model linking this paper

Cite arxiv.org/abs/2606.20997 in a model README.md to link it from this page.

Datasets citing this paper0

No dataset linking this paper

Cite arxiv.org/abs/2606.20997 in a dataset README.md to link it from this page.

Spaces citing this paper0

No Space linking this paper

Cite arxiv.org/abs/2606.20997 in a Space README.md to link it from this page.

Collections including this paper0

No Collection including this paper

Add this paper to acollectionto link it from this page.

Similar Articles

Beyond Prompt-Based Planning: MCP-Native Graph Planning-based Biomedical Agent System

arXiv cs.AI

BioManus is an MCP-native biomedical agent system that uses graph-scaffolded planning over structured biological capabilities instead of flat prompt-based tool retrieval, achieving better context efficiency and execution accuracy on biomedical benchmarks. The system introduces a BioinfoMCP Compiler to standardize heterogeneous bioinformatics tools and organizes them as a typed heterogeneous MCP graph for scalable reasoning.