causality-assessment

#causality-assessment

Optimizing Large Language Models for Causality Assessment in Pharmacovigilance: Developing a Performance Metric as Objective for Bayesian Hyperparameter Optimization

arXiv cs.CL ↗ · 2026-07-07 Cached

This paper presents a method to optimize GPT-5.2 temperature for Naranjo causality assessment in pharmacovigilance, achieving significant agreement improvements via Bayesian hyperparameter optimization with a novel composite metric (EWACS).

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causality-assessment

Optimizing Large Language Models for Causality Assessment in Pharmacovigilance: Developing a Performance Metric as Objective for Bayesian Hyperparameter Optimization

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