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Neuralink is exploring how clinical trial participants can control a powered wheelchair using their mind, detailing the process in a thread.
A joint investigation by Science and Retraction Watch has revealed an unreported death case in China involving gene editing therapy: A 6-year-old girl died after receiving a base editing therapy that was not approved by the National Medical Products Administration, raising ethical and regulatory concerns.
This paper presents RaDaR, a 32B open-source reasoning LLM trained on public and synthetic rare disease cases, which outperforms larger models like DeepSeek-R1 in diagnosis benchmarks and improves physician accuracy by 21.44 percentage points in a randomized trial.
A biotech company has dosed its first volunteer in a clinical trial for an experimental glaucoma treatment that uses cellular reprogramming to reverse age-related damage, part of a broader trend toward rejuvenation therapies.
LifeBioSciences has dosed the first patient in a Phase 1 trial of ER-100, an epigenetic restoration drug candidate for optic neuropathies, marking a milestone in the development of therapies for vision impairment.
First person treated in a gene therapy trial using partial reprogramming to rejuvenate cells, aiming to treat glaucoma by regenerating optic nerve neurons.
Life Biosciences has dosed its first patient with ER-100, a cellular rejuvenation therapy aiming to reverse age-related sight loss, in a first-ever human clinical trial approved by the FDA.
A new drug has shown the ability to 'functionally cure' many hepatitis B virus infections, offering hope for a significant breakthrough in treating this chronic disease.
Brian Armstrong announces that NewLimit has developed a prototype drug that reverses cellular aging in human cells, with a clinical trial scheduled for next year, and has raised $435M in Series C funding led by Founders Fund.
A 2025 review and pilot trial show that creatine supplementation raises brain energy levels and slows cognitive decline in early Alzheimer's patients by 30%, highlighting the supplement's overlooked neurological benefits.
A clinical trial found that the daily pill daraxonrasib doubles survival time for patients with pancreatic cancer, offering a significant breakthrough in treatment with fewer side effects compared to chemotherapy.
A clinical trial at the University of Nottingham developed special flavored chewing gums that restored taste and smell in a 44-year-old father who lost those senses years after contracting Covid-19; 67% of participants improved their sense of smell and 83% improved taste.
Early clinical trial results show that repurposing CAR-T cell therapy, originally used for cancer, can help control HIV long-term. Two patients achieved undetectable HIV levels after a single infusion and stopped medications, suggesting a potential functional cure.
Introducing the Chinese-American biostatistician C.C. Li, who in the 1950s promoted the popularization and standardization of the randomized double-blind principle in large-scale cancer drug clinical trials, making significant contributions to modern clinical trial methodology.
Researchers are testing CAR T cell therapy, originally designed for cancer, as a treatment for autoimmune diseases like multiple sclerosis, aiming to reset the immune system. The article follows a patient who received the experimental treatment.
A paralyzed patient received the world's first brain-computer interface implant in a higher-functioning cortical region, enabling interpretation of intent and planning. The procedure aims to restore movement and sensory feedback, marking a significant milestone in neuroscience.