obesity

A study from Columbia University finds that chronic mild sleep deprivation (about 80 minutes less per night) can lead to weight gain and increased sedentary time, challenging prior assumptions that only severe sleep loss affects weight.

This study uses single-cell RNA sequencing to map the developmental trajectory of human adipocytes, identifying 15 cell clusters and key signaling pathways such as IGF and FGF, offering potential therapeutic targets for obesity and metabolic disorders.