structural-proteomics

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#structural-proteomics

Co-folding model guided by structural proteomics

arXiv cs.LG · 2026-05-27 Cached

Introduces AIMS-Fold, an inference-time guided-diffusion framework that integrates cross-linking mass spectrometry (XL-MS) and hydrogen-deuterium exchange (HDX-MS) data to improve protein co-folding predictions for induced proximity drug targets.

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