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Researchers at the Arc Institute identified that STING agonists enter and kill T cells through the SLC7A1 arginine transporter, explaining the toxicity at high doses while still showing anti-tumor effects.
OpenAI's GPT-5 Pro helped immunologist Derya Unutmaz solve a three-year-old mystery about how glucose affects T cell specialization by suggesting that deoxyglucose interferes with IL-2 protein construction, leading to increased inflammatory Th17 cells.