Multi-Agent Systems in Emergency Departments: Validation Study on a ED Digital Twin
Summary
The paper presents a hybrid Discrete Event Simulation and Agent-Based Model framework for emergency departments, validated against real-world data, and integrates a multi-agent system for autonomous resource allocation optimization.
View Cached Full Text
Cached at: 05/14/26, 06:16 AM
# Multi-Agent Systems in Emergency Departments: Validation Study on a ED Digital Twin Source: [https://arxiv.org/abs/2605.13345](https://arxiv.org/abs/2605.13345) [View PDF](https://arxiv.org/pdf/2605.13345) > Abstract:Emergency departments \(ED\) face challenges in patient care and resource management\. We propose to explore optimization strategies in a realistic and flexible model and develop a hybrid Discrete Event Simulation \(DES\) and Agent\-Based Model \(ABM\) simulating highly configurable ED environments\. We specifically focus on the validation of the modeling approach\. We derive configurations for ED sizes, patient load, and staffing from real\-world studies\. We then validate the model expressivity by matching its key performance indicators and metrics with their values known from literature\. We proceed by implementing scientifically established and practice\-proven resource optimization strategies\. Comparing the documented real\-world outcomes with our model's results demonstrates that the DES\-ABM based simulation can effectively replicate real\-world ER dynamics under interventions\. We lastly integrate a Proof\-of\-Concept multi\-agent system \(MAS\) that can autonomously explore resource allocation strategies within the simulated ER environment based on a temporal ledger of ED event records\. This modular DES\-ABM\-MAS framework offers a powerful tool to explore resource optimization strategies in emergency departments\. ## Submission history From: Markus Wenzel \[[view email](https://arxiv.org/show-email/965541cc/2605.13345)\] **\[v1\]**Wed, 13 May 2026 11:04:23 UTC \(2,922 KB\)
Similar Articles
How DINO and SAM are Helping Modernize Essential Medical Triage Practices
Researchers at the University of Pennsylvania are using AI models like DINO and SAM to automate and modernize medical triage in emergency response.
Toward Vibe Medicine: A Self-Evolving Multi-Agent Framework for Clinical Decision Support
This paper presents VIBEMed, a multi-agent framework with a self-evolution mechanism and safety sandbox for robust clinical decision support, integrating specialized agents for diagnosis, treatment planning, and evolving clinical knowledge over time.
An Integrated Forecasting Prototype for Emergency Department Boarding Time to Support Proactive Operational Decision Making
This paper presents a multi-horizon time series forecasting framework for predicting emergency department boarding time using DLinear and NLinear models, and develops an MLOps web application prototype to support proactive operational decision making.
Treatment Response Optimized Clinical Decision Support AI System via Digital Twin Simulation
This paper presents an online adaptive clinical decision support AI system that integrates treatment effect estimation, digital twin simulation, and reinforcement learning to recommend treatments in a safe, clinician-supervised manner, validated on a synthetic simulator and the TCGA ovarian cancer dataset.
MedEvoEval: Evaluating Continual Evolution of Doctor Agents through Simulated Clinical Episodes
MedEvoEval is a longitudinal evaluation framework for doctor agents that simulates outpatient episodes, assessing how agents acquire evidence, use resources, and evolve across episodes through memory and reflection mechanisms.